Season 21 Details Casts Episode Lists of Season 21 Title Season 21 Genres Talk Comedy Air Date 2014-01-06 Episode Runtime 01 Hours 03 Minutes Season Number 21 Episode Count On Season 21 118 Production Companies Worldwide Pants, CBS Entertainment Productions, CBS Productions, CBS Studios David Letterman Self - Host Paul Shaffer Self -Musical Director Alan Kalter Self - Announcer (voice) Episode 1 2014-01-06 Lena Dunham; Max Greenfie... Episode 2 2014-01-07 Joel McHale; Marv Albert;... Episode 3 2014-01-08 Scarlett Johansson; John ... Episode 4 2014-01-09 Anderson Cooper; Bobby Mo... Episode 5 2014-01-10 Mindy Kaling; Jeff Altman... Episode 6 2014-01-13 Bill Cosby; Sleigh Bells... Episode 7 2014-01-14 Michael Strahan; Jennifer... Episode 8 2014-01-15 Kevin Hart; Mo Rocca; The... Episode 9 2014-01-16 Brian Williams; Rosanne C... Episode 10 2014-01-17 Don Cheadle; Myq Kaplan; ... Episode 11 2014-01-21 Andy Samberg; Michael B. ... Episode 12 2014-01-22 Martin Scorsese; Allison ... Episode 13 2014-01-23 Rachel Maddow; Spike Jonz... Episode 14 2014-01-24 Kevin Bacon; Pat McGann; ... Episode 15 2014-01-27 Louis C.K.; B.J. Ganem; A... Episode 16 2014-01-28 Eric Stonestreet; Nick Go... Episode 17 2014-01-29 Drew Brees; B.J. Novak; A... Episode 18 2014-01-30 Dr. Phil McGraw; Danny Ko... Episode 19 2014-01-31 Bill Murray; Eagulls... Episode 20 2014-02-03 Will Arnett; Broken Bells... Episode 21 2014-02-04 George Clooney; Sting... Episode 22 2014-02-05 Matt Damon; Lenny Kravitz... Episode 23 2014-02-06 Patrick Stewart; The Flam... Episode 24 2014-02-07 Regis Philbin; Ms. Lauryn... Episode 25 2014-02-17 Kevin Spacey, Amber Heard... Episode 26 2014-02-18 Sage Kotsenburg, Kate Mar... Episode 27 2014-02-19 Kaitlyn Farrington, Lupit... Episode 28 2014-02-20 Keri Russell, Terry Fator... Episode 29 2014-02-21 Pauley Perrette, Jeff Cal... Episode 30 2014-02-24 Kaley Cuoco-Sweeting, Dal... Episode 31 2014-02-25 Olympic Gold Medalist Ted... Episode 32 2014-02-26 Meredith Vieira, Band of ... Episode 33 2014-02-27 Stupid Human Tricks, Simo... Episode 34 2014-02-28 Jack (Jungle) Hanna, Jake... Episode 35 2014-03-03 Zach Braff, Sgt. Brendan ... Episode 36 2014-03-04 Michael Keaton, Phantogra... Episode 37 2014-03-05 Tom Selleck, Carrie Brown... Episode 38 2014-03-06 Tom Brokaw, Andrew Hadloc... Episode 39 2014-03-07 Mary-Louise Parker, Lenny... Episode 40 2014-03-10 Sen. John McCain, Little ... Episode 41 2014-03-11 Jason Bateman, Miles Tell... Episode 42 2014-03-12 Sylvester Stallone, Theo ... Episode 43 2014-03-13 Bryan Cranston, Melissa R... Episode 44 2014-03-14 Bill O'Reilly, Nick Griff... Episode 45 2014-03-24 Jimmy Carter... Episode 46 2014-03-25 Emma Watson, Nick Offerma... Episode 47 2014-03-26 Peter Dinklage, Hari Kond... Episode 48 2014-03-31 Cobie Smulders, Nick Cann... Episode 49 2014-04-01 Kristin Chenoweth, Amy Sc... Episode 50 2014-04-02 Bill Murray, Martha Stewa... Episode 51 2014-04-03 Johnny Depp, Kevin Drew... Episode 52 2014-04-04 Billy Crystal, Tony Hale,... Episode 53 2014-04-08 Rob Lowe, Brooklyn Decker... Episode 54 2014-04-09 Lindsay Lohan, Jamie Edwa... Episode 55 2014-04-21 Courteney Cox, Jimmie 'J.... Episode 56 2014-04-22 Stephen Colbert, Robin Ro... Episode 57 2014-04-23 Sally Field, Timothy Simo... Episode 58 2014-04-24 Neil Patrick Harris, Sara... Episode 59 2014-04-25 Piedmont Bird Callers, Mi... Episode 60 2014-04-28 Joel McHale, Vera Farmiga... Episode 61 2014-04-29 Lucy Liu, Ziggy Marley... Episode 62 2014-04-30 Kiefer Sutherland, Adam R... Episode 63 2014-05-01 Louis C.K., a performance... Episode 64 2014-05-02 Don Rickles, Carmen Lynch... Episode 65 2014-05-05 Shailene Woodley, Peyton ... Episode 66 2014-05-06 Jon Cryer, Elizabeth Olse... Episode 67 2014-05-07 Mariah Carey, Rick Harris... Episode 68 2014-05-08 James Franco, Idina Menze... Episode 69 2014-05-09 Nathan Fillion, Tom Drees... Episode 70 2014-05-12 Harry Connick Jr., Jesse ... Episode 71 2014-05-13 Jim Parsons, Julie Chen, ... Episode 72 2014-05-14 Barbara Walters, Elle Fan... Episode 73 2014-05-15 Adam Sandler, Thomas Hade... Episode 74 2014-05-16 Lea Michele, Andy Kindler... Episode 75 2014-05-19 Jack Hanna, Stephen Malkm... Episode 76 2014-05-20 Kid scientists, Sarah Sil... Episode 77 2014-05-21 Sgt. Kyle J. White, Judy ... Episode 78 2014-06-02 Donald Trump, Indianapoli... Episode 79 2014-06-03 Martin Short, John Oliver... Episode 80 2014-06-04 Anderson Cooper, Victor E... Episode 81 2014-06-05 Hugh Jackman, Joe List, E... Episode 82 2014-06-09 Kelsey Grammer, Willie Ne... Episode 83 2014-06-10 Dave Chappelle, Laura Pre... Episode 84 2014-06-11 Christopher Walken, Janel... Episode 85 2014-06-12 Regis Philbin, Paul Morri... Episode 86 2014-06-16 Susan Sarandon, Whitney C... Episode 87 2014-06-17 Olivia Wilde, Shep Gordon... Episode 88 2014-06-18 Dana Carvey, Ellie Kemper... Episode 89 2014-06-19 Paul Rudd, Jeff Altman, J... Episode 90 2014-06-23 Adam Levine, Gen. Frank J... Episode 91 2014-06-24 Melissa McCarthy, Rachell... Episode 92 2014-06-25 Mark Wahlberg, Ben Falcon... Episode 93 2014-06-26 Mark Ruffalo, Former Mari... Episode 94 2014-07-07 Halle Berry, Steve Young,... Episode 95 2014-07-08 Joan Rivers, Capital Citi... Episode 96 2014-07-09 Lizzy Caplan, Sleeper Age... Episode 97 2014-07-10 Michael Douglas, Paul Mor... Episode 98 2014-07-14 Kurt Russell, Hannibal Bu... Episode 99 2014-07-15 Jason Segel, Liv Tyler, T... Episode 100 2014-07-16 Emma Stone, Nathan Fielde... Episode 101 2014-07-17 Colin Firth, Tommy Johnag... Episode 102 2014-07-21 Jeff Daniels, Norah O'Don... Episode 103 2014-07-22 Ricky Gervais, Taylor Sch... Episode 104 2014-07-23 Eric Stonestreet, Brody D... Episode 105 2014-07-24 Staff Sgt. Ryan Pitts, Sh... Episode 106 2014-07-28 John C. Reilly, Rachelle ... Episode 107 2014-07-29 Chris Pratt, Rodrigo y Ga... Episode 108 2014-07-30 Zoe Saldana, Crash... Episode 109 2014-07-31 Julia Louis-Dreyfus, Simo... Episode 110 2014-08-18 Bruce Willis, the Gasligh... Episode 111 2014-08-19 Joseph Gordon-Levitt, Nov... Episode 112 2014-08-20 Kathy Griffin, Ken Burns,... Episode 113 2014-08-21 Serena Williams, Chadwick... Episode 114 2014-08-25 Michael Cera, dock diving... Episode 115 2014-08-26 Howie Mandel, EMA... Episode 116 2014-08-27 James McAvoy, Chris Russo... Episode 117 2014-08-28 Mike Myers, Bonnie McFarl... Episode 118 2014-09-02 Luke Wilson, Julie Chen, ...
