Season 22 Details Casts Episode Lists of Season 22 Title Season 22 Genres Talk Comedy Air Date 2014-09-02 Episode Runtime 01 Hours 03 Minutes Season Number 22 Episode Count On Season 22 139 Production Companies Worldwide Pants, CBS Entertainment Productions, CBS Productions, CBS Studios David Letterman Self - Host Paul Shaffer Self -Musical Director Alan Kalter Self - Announcer (voice) Episode 1 2014-09-02 Luke Wilson, Julie Chen, ... Episode 2 2014-09-03 Kristen Wiig, Sen. Elizab... Episode 3 2014-09-04 Steve Buscemi, Indy Car S... Episode 4 2014-09-05 Tina Fey, Moody McCarthy,... Episode 5 2014-09-08 Bill Maher, Henrik Lundqv... Episode 6 2014-09-09 Michael Strahan, Richard ... Episode 7 2014-09-10 Dr. Phil, Katharine McPhe... Episode 8 2014-09-11 Jason Bateman, Billy Eich... Episode 9 2014-09-12 Mindy Kaling, Jake Johann... Episode 10 2014-09-22 Mark Harmon, "Jungle" Jac... Episode 11 2014-09-23 Denzel Washington, Lenny ... Episode 12 2014-09-24 Kelly Ripa, Jim Gaffigan,... Episode 13 2014-09-25 Jerry Seinfeld, Michael J... Episode 14 2014-09-26 Ted Danson, Andrew Norell... Episode 15 2014-09-29 Neil Patrick Harris, Jami... Episode 16 2014-09-30 John Oliver, Maggie Q, Bl... Episode 17 2014-10-01 Bill O'Reilly, Cristin Mi... Episode 18 2014-10-02 Johnny Galecki, Andre Ben... Episode 19 2014-10-03 Mariska Hargitay, Simon A... Episode 20 2014-10-06 Aziz Ansari, Tom Dreesen... Episode 21 2014-10-07 Robert Downey Jr., Sarah ... Episode 22 2014-10-08 Anderson Cooper, Gina Rod... Episode 23 2014-10-09 Robert Duvall, Elle Fanni... Episode 24 2014-10-10 Chelsea Handler; Keegan-M... Episode 25 2014-10-13 Russell Brand, Dave Grohl... Episode 26 2014-10-14 Michael Keaton, Foo Fight... Episode 27 2014-10-15 Bill Murray, Foo Fighters... Episode 28 2014-10-16 Tom Selleck, Jenny Slate,... Episode 29 2014-10-17 Jessica Chastain, Lenny M... Episode 30 2014-10-27 Amy Poehler, Sen. Jeff Fl... Episode 31 2014-10-28 Taylor Swift, Tom Mison... Episode 32 2014-10-29 Jim Carrey, David Tennant... Episode 33 2014-10-30 Brian Williams, Perfume G... Episode 34 2014-10-31 Keith Olbermann, Brian Re... Episode 35 2014-11-03 Martin Short, Father John... Episode 36 2014-11-05 Jennifer Lopez, Rob Riggl... Episode 37 2014-11-06 Whoopi Goldberg, Jimmy Pa... Episode 38 2014-11-07 Amy Schumer, Jeff Caldwel... Episode 39 2014-11-10 Katie Holmes, Alex Zanard... Episode 40 2014-11-11 Steve Carell, Martha Stew... Episode 41 2014-11-12 Jennifer Lawrence, Boris ... Episode 42 2014-11-13 Jon Stewart, Shawn Mendes... Episode 43 2014-11-14 Kristin Chenoweth; Chris ... Episode 44 2014-11-17 Jason Sudeikis, Allison J... Episode 45 2014-11-18 Stupid Pet Tricks, Charli... Episode 46 2014-11-19 Regis Philbin, Hundred Wa... Episode 47 2014-11-20 Edward Norton, Jessye Nor... Episode 48 2014-11-21 Norman Lear, TV on the Ra... Episode 49 2014-11-24 Seth Rogen, Amy Sedaris... Episode 50 2014-11-25 Emily Blunt, Adam Resnick... Episode 51 2014-11-26 Jake Gyllenhaal, Dr. John... Episode 52 2014-12-08 Joaquin Phoenix, Cristela... Episode 53 2014-12-09 Ben Stiller, Olivia Munn,... Episode 54 2014-12-10 Meryl Streep, Rebel Wilso... Episode 55 2014-12-11 Chris Rock, Sting... Episode 56 2014-12-12 Jamie Foxx, Robert Klein,... Episode 57 2014-12-15 Emma Stone Top, Marcus Ma... Episode 58 2014-12-16 New Holiday Toys, Anna Ke... Episode 59 2014-12-17 Tom Brokaw, Will Nelson &... Episode 60 2014-12-18 Rosie O’Donnel,l Jeff A... Episode 61 2014-12-19 Jay Thomas, Josh Brolin, ... Episode 62 2015-01-05 Kathy Griffin, David Oyel... Episode 63 2015-01-06 Ethan Hawke, Allison Will... Episode 64 2015-01-07 Julianne Moore, Catfish &... Episode 65 2015-01-08 Donald Trump, Chelsea Per... Episode 66 2015-01-09 Michael Somerville, Nicol... Episode 67 2015-01-12 Gordon Ramsay, Adam Devin... Episode 68 2015-01-13 Anderson Cooper, Shovels ... Episode 69 2015-01-14 Amanda Peet, Ryn Weaver... Episode 70 2015-01-15 Larry David, Dan Patrick,... Episode 71 2015-01-16 Urban Meyer, Johnny Beehn... Episode 72 2015-01-26 Louis CK, Nicolle Wallace... Episode 73 2015-01-27 Andrew Luck, Oscar Isaac,... Episode 74 2015-01-28 Viola Davis, Ben Schwartz... Episode 75 2015-01-29 John Oliver, Mayim Bialik... Episode 76 2015-01-30 Aziz Ansari, Brian Kiley,... Episode 77 2015-02-02 Jack Hanna, Sharon Jones ... Episode 78 2015-02-03 Dr. Phil McGraw, Robin Tu... Episode 79 2015-02-04 Ryan Reynolds, Dierks Ben... Episode 80 2015-02-05 Martin Short, Bettye Lave... Episode 81 2015-02-06 Sienna Miller, Andy Kindl... Episode 82 2015-02-09 Steve Carell, Dr. Cornel ... Episode 83 2015-02-10 Courtney Love, Chris Elli... Episode 84 2015-02-11 Bill Belichick, Elisabeth... Episode 85 2015-02-12 Tom Hanks, Sturgill Simps... Episode 86 2015-02-13 Bill Hader, Pat McGann, S... Episode 87 2015-02-16 Matthew Perry, Adam Scott... Episode 88 2015-02-17 Dakota Johnson, David Toc... Episode 89 2015-02-18 Will Smith, Grizfolk... Episode 90 2015-02-19 Don Cheadle, Ilana Glazer... Episode 91 2015-02-20 Kid Scientists, Sean Haye... Episode 92 2015-02-23 Helen Mirren, the 2015 Da... Episode 93 2015-02-24 Matthew Broderick, Ellie ... Episode 94 2015-02-25 Julianna Margulies, Eric ... Episode 95 2015-03-09 Kevin Spacey, Lily James,... Episode 96 2015-03-10 Patricia Arquette, Will B... Episode 97 2015-03-11 Kelsey Grammer, Stevie Wo... Episode 98 2015-03-12 Lena Dunham, Bobby Cannav... Episode 99 2015-03-13 Kevin Bacon, Jimmie Walke... Episode 100 2015-03-16 Shailene Woodley, Dr. Cor... Episode 101 2015-03-17 Will Ferrell, Glen Hansar... Episode 102 2015-03-18 Norm MacDonald, Theo Jame... Episode 103 2015-03-23 Ben Stiller, Tove Lo... Episode 104 2015-03-24 Bill O'Reilly, Aubrey Pla... Episode 105 2015-03-25 James Franco, Jake Johann... Episode 106 2015-03-30 Neil Patrick Harris, Char... Episode 107 2015-03-31 David Duchovny, Josh Gad,... Episode 108 2015-04-01 Sen. Al Franken, Billy Ei... Episode 109 2015-04-02 Kelly Ripa, Aasif Mandvi,... Episode 110 2015-04-03 Mike Myers, Nick Griffin,... Episode 111 2015-04-13 Sarah Jessica Parker, Jul... Episode 112 2015-04-14 Billy Crystal, Chris Russ... Episode 113 2015-04-15 Michael J. Fox, Iron & Wi... Episode 114 2015-04-16 Kevin James, Tom Dreesen,... Episode 115 2015-04-17 Alec Baldwin, John Mayer... Episode 116 2015-04-20 John Travolta, Amy Schume... Episode 117 2015-04-21 Piedmont Bird Callers, Pa... Episode 118 2015-04-22 Bruce Willis, Dawes... Episode 119 2015-04-23 Robert Downey Jr., Chris ... Episode 120 2015-04-24 Jerry Seinfeld, Jason Isb... Episode 121 2015-04-27 Scarlett Johansson, John ... Episode 122 2015-04-28 Michael Keaton, Future Is... Episode 123 2015-04-29 Jack Hanna, John Popper... Episode 124 2015-04-30 First Lady Michelle Obama... Episode 125 2015-05-01 Steve Martin, Emmylou Har... Episode 126 2015-05-04 President Barack Obama, W... Episode 127 2015-05-05 Reese Witherspoon, Nathan... Episode 128 2015-05-06 Martin Short, Norah Jones... Episode 129 2015-05-07 Tina Fey, First Aid Kit... Episode 130 2015-05-08 Ray Romano, Brian Regan, ... Episode 131 2015-05-11 Howard Stern, Don Rickles... Episode 132 2015-05-12 Bill Clinton, Adam Sandle... Episode 133 2015-05-13 Julia Roberts, Paul Shaff... Episode 134 2015-05-14 Al Pacino, George Clooney... Episode 135 2015-05-15 Oprah Winfrey, Norm Macdo... Episode 136 2015-05-18 Tom Hanks, Eddie Vedder... Episode 137 2015-05-19 Bill Murray, Bob Dylan... Episode 138 2015-05-20 The Final Late Show with ... Episode 149 2015-05-20 Episode 149...
