Osmosis Jones Every body needs a hero. A white blood cell policeman, with the help of a cold pill, must stop a deadly virus from destroying the human they live in, Frank. Details Casts Title Osmosis Jones Release Date 2001-08-10 Runtime 01 Hours 35 Minutes Genres Adventure Animation Action Comedy Family Production Companies Conundrum Entertainment, Warner Bros. Pictures Production Countries United States of America Chris Rock Osmosis Jones (voice) Laurence Fishburne Thrax (voice) David Hyde Pierce Drix (voice) Brandy Norwood Leah (voice) Bill Murray Frank Detorre Molly Shannon Mrs. Boyd William Shatner Mayor Phlegmming (voice) Ron Howard Tom Colonic (voice) Sherry Lynn (voice) Mickie McGowan Additional Character Voi? Chris Elliott Bob Elena Franklin Shane Detorre Kid Rock Kidney Rock Uncle Kracker Kidney Rock (voice) Carlos Alazraqui Additional Character Voi? Rodger Bumpass Additional Character Voi? Richard Steven Horvitz Additional Character Voi? Danny Mann Additional Character Voi? Mickie McGowan Additional Character Voi? Jonathan Adams Additional Character Voi?